A new role for Rrm3 in repair of replication-born DNA breakage by sister chromatid recombination
نویسندگان
چکیده
منابع مشابه
A new role for Rrm3 in repair of replication-born DNA breakage by sister chromatid recombination
Replication forks stall at different DNA obstacles such as those originated by transcription. Fork stalling can lead to DNA double-strand breaks (DSBs) that will be preferentially repaired by homologous recombination when the sister chromatid is available. The Rrm3 helicase is a replisome component that promotes replication upon fork stalling, accumulates at highly transcribed regions and preve...
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ژورنال
عنوان ژورنال: PLOS Genetics
سال: 2017
ISSN: 1553-7404
DOI: 10.1371/journal.pgen.1006781